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Niacin (B3)

Also called: Vitamin B3, nicotinic acid, niacinamide, nicotinamide

Needed to make NAD, a molecule every cell uses for energy and repair. It comes in two main forms that act very differently: niacin can cause flushing and affects cholesterol, while niacinamide does neither.

Commonly used for

  • Energy metabolism
  • Skin health (niacinamide)
  • Cholesterol, only under a prescriber's care (niacin)
  • General B-complex support

Found naturally in

  • Chicken and turkey
  • Tuna and salmon
  • Peanuts
  • Mushrooms
  • The body also makes some from tryptophan in protein foods

Label red flags

  • 'Niacin' on the label without saying whether it is nicotinic acid or niacinamide
  • Sustained-release, time-release, or slow-release niacin
  • 'Flush-free' or 'no-flush' niacin sold for cholesterol

Check with a provider

  • Liver disease, heavy alcohol use, or signs of liver strain such as nausea, dark urine, or yellow skin or eyes. Stop and get checked.
  • Taking a statin or other cholesterol medicine. Adding high-dose niacin can raise the risk of muscle and liver problems.
  • Diabetes or prediabetes, since high-dose niacin can raise blood sugar
  • Gout or a stomach ulcer, which high-dose niacin can make worse
  • Pregnant or breastfeeding. The amount in a prenatal is fine. Avoid high-dose niacin.

Supplements that contain it

Dr. Lesher, ND

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